Albert Krastanov, PhD DSc, Professor



University of Food Technology
Dept. Biotechnology
Office 258, Bl. 1
26 Maritza Blvd
4000 Plovdiv

Phone: +359 32 603 630
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.



Professional experience

2008 Profesor , Dept. of Biotechnology, UFT

2007 Doctor of Science

2004 Visiting-Professor, Dep. of Biotechnology, Vellore Institute of Technology, India

2001-2002 Visiting-Professor, International Center for Biotechnology, Osaka University, Japan

2001 Associate Professor, Dept. of Biotechnology, UFT

1994 -2001 Senior Assistant Professor, Dept. of Biotechnology, UFT

1988 -1994 Assistant Professor, Dept. of Microbiology and Biotechnology, UFT

1987 -1988 Lecturer, College of Biotechnology, Razgrad

1985 -1987 Research Assistant, Institute of Industrial Microbiology (“Actavis”), Razgrad

Courses taught

Industrial Enzymology

Applied Enzymology

Separation and analysis of Bio-products

Enzyme engineering


Students advised (last 5 years)

Graduate students – 30, PhD students – 5



Krastanov A., Biochemistry, 1987

Argirova-Getova Tr., Krastanov A., Biochemistry, 1990

Krastanov A., Immobilized microbial cells, ASK, 1995

Gargova S., Krastanov A., Industry Enzymology, UFT,  1997

Gargova S., Krastanov A., Stoilova I. Handbook of enzymology, UFT - Plovdiv, 2008

G. Jayaraman, A. Krastanov, LAB MANUAL OF BIOCHEMISTRY, India, 2009


Selected publications

Krastanov A. (2000) Removal of phenols from mixtures by co-immobilized laccase/tyrosinase and Polyclar adsorption, Journal of Industrial Microbiology & Biotechnology, 24: 1-6

Lante A., Crapisi A., Krastanov A., Spettoli P. (2000) Biodegradation of phenols by Laccase immobilized in a membrane reactor, Process Biochemistry, 36: 51-58

Krastanov A., Yoshida T. (2003) Production of Palatinose using Serratia plymuthica cells immobilized in Chitosan, Journal of Industrial Microbiology and Biotechnology, 30: 593-598

Denkova Z., Krastanov A., Murgov I. (2004) Immobilized lactic acid bacteria for application as dairy starters and probiotic preparations, Journal of General and Applied Microbiology, 50: 107-114

Stoilova I., Krastanov A., Stanchev V., Daniel D., Gerginova M. and Z. Aleksieva (2006) Biodegradation of high amounts of phenol, catechol, 2,4-dichlorophenol and 2,6-dimethoxyphenol by Asperillus awamori cells, Enzyme and Microbial Technology, 39: 1063-10

Jirovetz L., Buchbauer G., Stoilova I., Stoyanova A., Krastanov A., Schmidt E. (2006) Chemical Composition and antioxidant properties of Clove Leaf Essential Oil, Journal of Agricultural and Food Chemistry, 54: 6303-6307

Krastanov A., Blazheva D., Yanakieva I., Krachanova M. (2006) Conversion of sucrose into palatinose by immobilized Serratia plymuthica cells, Enzyme and Microbial Technology, 39: 1306-1312

Stoilova I., Krastanov A., Stoyanova A., Denev P., Gargova S. (2006)  Antioxidant activity of a Ginger extract (Zingiber officinale), Food Chemistry, 102: 764-770

Krastanov A., Blazheva D. and Stanchev V. (2007) Sucrose conversion into palatinose with immobilized Serratia plymuthica cells in a hollow-fibre bioreactor, Process Biochemistry, 42: 1655-1659

Stoilova I. and Krastanov A. (2007) Overproduction of laccase and pectinase by microbial associations in solid substrate fermentation, Applied Biochemistry and Biotechnology, 149(1): 45-51

Stanchev V., Stoilova I. and Krastanov A. (2008) Biodegradation dynamics of high catechol conventrations by Apsrgillus awamori, Journal of Hazardous Materials, 154: 396-402   

Ivan Gitsov, James Hamzik, Joseph Ryan, Arsen Simonyan, James Nakas, Shigetoshi Omori, Albert Krastanov, Tomer Cohen, Stuart Tanenbaum (2008) Enzymatic Nano-reactors for Environmentally Benign Biotransformations. 1. Formation and Catalytic Activity of Supramolecular Complexes of Laccase and Linear-Dendritic Block Copolymers, Biomacromolecules, 9: 804-811



Biodegradation of toxic environmental pollutants from filamentous fungi. VU-B-207/06 contract with MES (2006-2009)

Molecular and biochemical analyzes of Antarctic fungal strains: examination of biodegradation ability of phenolic and polyaromatic environmental pollutants. Contract № 02/74-2009 DTC (2009-2012)

Threeterpenoids separation from plant waste materials and their biological activity determination. Contract 8/10-N (2010-2011)

Immobilization of proteolytic enzymes on polyurethane membranes. Bilateral research project with EADS DEUTSCHLAND GMBH - Germany (2010-2012)

Aerodynamic surfaces by advanced multifunctional coatings. collaborative project with EADS DEUTSCHLAND GMBH–Germany and SEVEN FRAMEWORK PROGRAMME (2011-2013)



1992 "The Union of Scientists in Bulgaria " 

1994 "The New York Academy of Sciences " 

2002 "The society of  the Biotechnologists in Bulgaria " 

2007 "American Chemical Society " 


Memberships, expert commissions, etc
"Engineering in Life Science" - Germany 

"Ecological engineering and environment protection" - Bulgaria 

"Biotechnology & Biotechnological equipment" - Bulgaria



1990 (5 months) Dept. of Chemical Enzymology, Moscow University, Russia (Protein engineering; Biosynthesis of enzymes; Downstream processes).

1997-1998 (12 months) "Post-doc" Dept. of Biotechnology, Padova University, Italy (Purification and immobilization of enzymes and peptide antibiotics; Enzyme kinetic; Applied biocatalysis; Food technology).

2000 (6 months) "Post-doc" Division of Biological Sciences, Institute of Scientific and Industrial Research, Osaka University, Japan (Enzyme function and kinetic; Purification of Enzymes; Spectroscopy Studies; Site-directed mutagenesis).

2001-2002 (6 months) MIF - grant International Center for Biotechnology, Osaka University, Japan (Microbial production of Enzymes, Immobilization of microbial cells and application for Palatinose production)

2003 (5 months) Dep. of Biochemistry, Biophysics and Molecular Biology, Iowa State University, USA (Cholesterol reductase purification and assay, transformation of cholesterol with immobilized cells)

2004 (4 months) Dep. of Biotechnology, Vellore Institute of Technology, India (Biosynthesis, purification and characterization of thermostable proteinase and tannase)

2005-2006 (6 months) "FULBRIGHT" GRANT State University of New York, USA (Preparation and characterization of immobilized and co-immobilized enzymatic systems with copolymer/enzyme constructs; Nondestructive Regioselective Modification of Laccase by Linear-Dendritic Copolymers)

2009 (3 months) JSPS GRANT Department of Biotechnology, Osaka University, Japan (METABOLOMICS)


Related courses and short visit:

1996 - Laboratory of Protein Chemistry, INRA – Nantes, France (Recent purification methods in protein chemistry and biochemistry

1996 - Advanced course of Applied Biocatalysis, Balatonfured, Hungary

1999 - Institute of Molecular Biology & Biotechnology, Heraklion, Greece (Methods in molecular biology and genetic)

2009 - Dept. of Biotechnology, Padova University, Italy (Immobilization of Bifidobacteria for novel Fructooligosaccharides production)

           Reviews over 10
           Reviews abroad over 22
           Citations over 340

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